Seattle will take the field without the ailing DJ Metcalf, perhaps the league's most dangerous WR. His absence could cripple the offense. On the other side, the Cardinals are scoring just 15 ppg since ambushing the Cowboys a month ago. They cannot count on motoring much the ground; the Seahawks allow an NFL-low 3.2 yards per carry. The last two Seattle outings have generated 27 and 30 points -- and Metcalf participated in both.

JSN is now healthy, he’s very good and DK Metcalf may not even play! AZ is not great v. The pass and I’ll bet the rookie gets some love today

Walker has scored in 4 straight, he is the lead dog and AZ is one of the 5 worst against the run. I project 3-4 TDs for Sea and at least 1 for Walker.

First-round rookie Jaxon Smith-Njigba played his first game last week without a cast on his wrist, and the results were promising: a season-high 53 snaps, five targets, four catches, 48 yards. JSN also got wide open deep in Cincinnati territory late in the game, but Geno Smith scrambled, a mistake Smith owned up to afterward. Now Smith-Njigba gets to face Arizona's weak pass defense in Seattle, with coaches talking up his massive potential. Look for at least 35 receiving yards Sunday.

Marquise Brown has been inefficient this year, but he continues to enjoy an elite target share and air yard share. This week he'll get another negative game script against a Seattle team that has talent in the secondary, but which has also given up a ton of yardage to receivers. I expect regression to the mean with respect to the efficiency which should mean Marquise Brown comfortably clears this yardage number.

Michael Wilson doesn’t receive a ton of targets. However, he has big-play upside. That has enabled him to record at least 56 receiving yards in four of his six games. He only had more than four targets in one of those four games. The Seahawks have given up the fifth-most passing yards per game in the league, so Wilson could blow by this over.

As a 7.5 point dog, the Cardinals will play plenty of this game in the air. Michael Wilson is averaging over 17 yards per reception. The Sportsline Model projects him for 40 yards. This Seattle defense can be shaky at times. Look for Wilson to continue to grow his role on this offense and hit this prop on two receptions.

Kenneth Walker has scored a TD in four consecutive games and has 6 on the season. He will face a Cardinals team 4th most rushing yards to opposing RBs. Seahawks RB2 Zach Charbonnet has yet to practice this week which could mean an even larger workload for Walker who is averaging just under 20 touches per game over his past four games. Kenneth Walker looks like he's in line for a big day. I like his chances to get in the endzone.

The Cardinals have been a nice story and played well above expectations over the first 3-4 weeks of the season. They came crashing back to earth last week and have really cratered since losing the centerpiece of their offense James Conner. They'll be traveling to Seattle to take on a Seahawks team coming off a loss (they should have won). I believe Seattle has one of the most talented rosters in the NFL and are starting to play like it as well. I think this is a massive mismatch and I like Seattle win by double digits.

The Seahawks were unlucky not to beat the Bengals after largely dominating the game. They have the best run defense in the league, which should be able to handle a toothless Cardinals rushing attack without James Conner. Seattle has plenty of talent and depth in the secondary as well, so it'll be a struggle for Arizona to score points. The Seahawks should bounce back on the scoreboard as their offense looked good last week despite the lack of points. I have this line projected at Seahawks -9 in my power ratings, and this stands out as low to me after the Rams closed at -7 vs. Arizona and easily covered.

This is my favorite play of the week. The Cardinals have no run game without James Conner and Josh Dobbs has reverted to form the past two games, throwing three INTs with passer ratings in the 50s. He'll face an angry Seahawks team that dominated the stats but lost a squeaker at Cincinnati. Seattle's secondary is formidable with Riq Woolen, Devon Witherspoon, Jamal Adams and Quandre Diggs. Just like Joe Burrow enjoyed his best game against Arizona's undermanned secondary, Geno Smith should pick apart the Cardinals. Look for Arizona to drop its fourth straight by double digits.

Keaontay Ingram received the majority of the backfield touches last week but I'm not sure if that will be the case this week against Seattle. Damian Williams, Emari Demercado, and even Rondale Moore also handled work. Don't forget about Josh Dobbs who accounts for a fairly significant share of Arizona's rushing attempts as well. Ingram averages a career 2.3 YPC and will face a Seattle run defense that is 1st in Defensive run grade and top 5 in nearly every defensive rushing metric. This is a tough spot against on the road for Ingram and the Cardinals ground game.