It's going to be a chilly opening day at Wrigley Field at 44° with winds blowing in at 10 mph. Under is probably the way to go, but I think sticking with the Padres, who have a 7-0 start, is the way to go here at plus-145. Randy Vasquez didn't allow a run in six innings against the Braves, allowing only four hits, and that follows up a great outing on September 28 against Arizona, 5-0, in a game that Arizona had to win. I know there's going to be some opening day emotions for the Cubs, but the Padres are 7-0 and playing very well. Padres to win.