Head coach Deion Sanders and the No. 20 Colorado Buffaloes (6-2, 4-1) look to keep pace in the Big 12 standings when they travel to take on the Texas Tech Red Raiders (6-3, 4-2) on Saturday. Kickoff at Jones AT&T Stadium in Lubbock, Texas is scheduled for 4 p.m. ET. The Buffs are coming off a bye in Week 10, but notched a 34-23 win over Cincinnati in their last outing. Shedeur Sanders threw for 323 yards and two touchdowns in the win. Heisman Trophy candidate Travis Hunter continues to excel on both sides of the ball and caught both of Sanders' touchdown passes against the Bearcats. Texas Tech is looking to build off its 23-22 road win over Iowa State in its last game. CU is 6-2 and Texas Tech is 5-3-1 against the spread this season. 

The Buffs are favored by 4.5 points in the latest Arizona vs. Colorado odds via SportsLine consensus, while the over/under for total points scored is 62.5. Colorado is a -184 (risk $184 to win $100) favorite on the money line, with Texas Tech listed as a +151 underdog (see up-to-date odds for every game this week on our college football odds page). 

Before you make any Colorado vs. Texas Tech picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is a NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has destroyed the sportsbooks in college football the last two seasons, netting a whopping 71.5 units while posting a 196-118-4 record since Week 1 of the 2023 season. All of his picks have been featured on his SportsLine expert page or in his weekly bylined articles. Anyone who followed his picks is WAY UP!

Now, Kaylor has locked in a confident against-the-spread pick for Colorado vs. Texas Tech in their Week 11 Big 12 matchup in Lubbock. We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Colorado vs. Texas Tech in their Week 11 matchup in Lubbock on Saturday, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who is 196-118-4, returning $7,150 for $100 bettors, betting on college football since Week 1 of the 2023 season, and find out!

Be sure to follow Jimmie (@jimmiekaylor) on Twitter for notifications about picks changes/updates