I'm continuing to ride some divisional trends in my initial plays for Week 6. 

We have some strong signals that have held over a number of years and a grouping of teams who usually tend to bring out the worst in each other. In several of these rivalry games, the games tend to be ugly with limited offensive acumen. I expect defense to carry the day.

Before you make your Week 6 picks, you'll want to see what NFL expert Jason La Canfora has to say. La Canfora has broken the games down and found a number of early best bets, including a play on the Bills-Jets game. You NEED to see his analysis before locking in any NFL picks of your own.

Which lines are worth jumping on right now, and what are the best plays for Bills-Jets? Join SportsLine right now to see Jason La Canfora's NFL Week 6 betting primer!