The Detroit Lions lost for the first time since Week 2 last Sunday, but that concern pales in comparison to the rash of season-ending injuries they continue to face. Running back David Montgomery is out for the year after suffering a knee sprain in Week 15 and can be added to the more than two-dozen players on injured reserve for Detroit this season. Top defensive tackle Alim McNeill and cornerback Carlton Davis III joined Montgomery in the loss against Buffalo. Though Detroit's offense is as potent as any in the league, will the M*A*S*H defense be able to stop any opponent in the playoffs? First the Lions play the struggling Chicago Bears in Week 16, losers of eight straight games. Can Detroit hold its tenuous lead at the top of the NFC North with a win as 7-point road favorites, one of the largest Week 16 NFL spreads?

Before you lock in any NFL picks or any NFL score predictions, you NEED to see what SportsLine expert Eric Cohen has to say. He just locked in his exact NFL score predictions for every game this week, which could mean a HUGE payday north of 100-1 if any of them hit.

Cohen, host of the weekly Early Edge NFL Prop Show on YouTube, is evaluating the entire Week 16 NFL slate and delivers score predictions and logic for each matchup. After a 14-2 record in Week 15, he is now 123-53 (70%) since Week 4. Anyone who has followed Cohen's NFL predictions is up BIG! 

We can tell you that Cohen likes the Rams (-3.5, 46.5) to beat the Jets as road favorites in Week 16. "One of the most interesting games on the slate this week. The Rams are finding ways to win ugly and/or weird games and I'd expect another one with the Jets this weekend. New York's offense has looked pretty darn good of late and should make this a fun game. But in true Jets fashion, do you really expect them to beat a good team? I don't...Rams 28, Jets 24."

In addition, Cohen is calling for high-scoring games this week, including in both AFC North divisional battles! Nailing these results is key to making profitable Week 16 NFL picks. You ABSOLUTELY NEED to see which game it is before locking in any Week 16 NFL score predictions!

Who wins every Week 16 NFL game, and which games are must bets for the over? ... Join SportsLine now to get Eric Cohen's Week 15 NFL score predictions and find out today!