The NFL Week 16 schedule features multiple high-profile matchups with five teams favored by seven points or more and two teams favored by double digits in the latest Week 16 NFL odds. The Sunday NFL slate features 12 games, including Cowboys vs. Buccaneers (-4, 48.5) on Sunday Night Football. Among the most notable NFL matchups during the day are Eagles (-3.5, 45.5) vs. Commanders, Vikings (-3, 42.5) vs. Seahawks, 49ers vs. Dolphins (-1, 44.5). With so many games on the Week 16 NFL schedule and parity around the league at an all-time high, finding value in the Week 16 NFL point spreads can require a different perspective.

Before making your Week 16 NFL picks and bets, you NEED to see what sides the Las Vegas sharps and professional football bettors are backing.

Sharp money bettors are notorious in Las Vegas for finding value in point spreads and betting lines that casual bettors may not see. These professional bettors are respected by sportsbooks in Vegas and all around the world, and their betting action often causes bookmakers to change their lines. 

Jay Kornegay, EVP of the Westgate SuperBook in Las Vegas, joined SportsLine NFL expert Jimmie Kaylor to share who the Vegas sharps are backing in the Week 3 NFL odds. Kornegay is a longtime oddsmaker at the SuperBook, and has been a key player on the Vegas bookmaking scene for more than 25 years. He was inducted into the Sports Betting Hall of Fame Class of 2024. 

Since Week 3 (when this article was first published), the sharps have been crushing the sportsbooks, going a combined 17-10 against the spread on their NFL picks!

For Week 16, one of the Sharp Money plays the SuperBook has taken is the Minnesota Vikings (-3, 42.5) covering against the Seattle Seahawks on Sunday. The Seahawks are coming off a blowout loss at home to the Green Bay Packers, while the Vikings keep finding ways to win while putting together their current seven-game winning streak. 

The Vegas sharps have also targeted two other NFL games and already locked in their against the spread picks, including an underdog covering in a matchup between teams looking to keep their respective postseason hopes alive! You ABSOLUTELY need to see these picks before locking in any NFL picks of your own.

What are the top NFL picks for Week 16, and which massive underdog is getting ALL the attention? ... Join SportsLine now to see the top Week 16 NFL picks and best bets from respected Vegas sharps and find out!