After suffering their first loss of the season last week, the San Francisco 49ers will visit the Minnesota Vikings on Monday Night Football. Vikings receiver Justin Jefferson (hamstring) and 49ers receiver Deebo Samuel (shoulder) are out. 49ers running back Christian McCaffrey (oblique) is questionable, which could significantly impact your NFL DFS strategy. Before setting your Week 7 NFL DFS lineups for Monday Night Football on sites like DraftKings and FanDuel, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings.

He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once! Now, McClure has turned his attention to 49ers vs. Vikings on Monday Night Football and locked in his top daily Fantasy football picks. 

We can tell you one of McClure's top NFL DFS picks for Monday Night Football is 49ers receiver Brandon Aiyuk. Part of McClure's optimal NFL DFS strategy also includes rostering Vikings running back Alexander Mattison, who has 424 scrimmage yards and two touchdowns this season.

McClure is also targeting a player who could go off for MASSIVE numbers on Monday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Monday Night Football, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!