The 2023 Week 12 NFL schedule opens with the traditional three-game slate on Thanksgiving Day. The slate starts with Lions vs. Packers at 12:30 p.m. ET, followed by Cowboys vs. Commanders at 4:30 p.m. ET and 49ers vs. Seahawks at 8:20 p.m. ET. The NFL DFS player pool features many high-end, proven fantasy options, mixed with young, high upside players, meaning there will be plenty of tough decisions to be made when building NFL DFS lineups. Should perennial Pro Bowl candidates like Dak Prescott, Christian McCaffrey, CeeDee Lamb, Amon-Ra St. Brown, or George Kittle be a part of your Thanksgiving NFL DFS lineups or NFL DFS stacks? What about young stars like Jahmyr Gibbs, Jordan Love, Zach Charbonnet, and Sam Howell? Running backs Aaron Jones (knee) and Kenneth Walker III (oblique) have been ruled out.

Before locking in any playoff NFL DFS lineups or NFL DFS stacks for Thanksgiving Day on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks all season in 2022. He was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15.

This year, Kaylor has been all over players like Justin Jefferson (11-159), D'Andre Swift (175-1), DeVonta Smith (4-132-1), T.J. Hockenson (7-66-2), D.J. Moore (8-230-3), David Montgomery (121-3), Ja'Marr Chase (12-141), Alvin Kamara (12-91, 76), Jordan Addison (7-123-2), Jahmyr Gibbs (152-1, 5-37), and Javonte Williams (79, 3-31-1) in single-game slates. Anyone who followed his picks cashed in BIG!

Now, Kaylor has turned his attention to the three-game Thanksgiving Day slate to open Week 12 and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for Thanksgiving Day is Dallas quarterback Dak Prescott. Part of Kaylor's optimal NFL DFS strategy also includes rostering 49ers tight end George Kittle. "Kittle has a lengthy history of success against the Seahawks, and he has become one of Brock Purdy's favorite targets," Kaylor told SportsLine.

Kaylor is also targeting another under-the-radar player for Thanksgiving Day who could post HUGE numbers and carry your lineups to victory! His NFL DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups!

Be sure to follow Jimmie (@jimmiekaylor) on Twitter for notifications about rosters changes/updates

What are the top NFL DFS picks for the Thanksgiving Day NFL slate on FanDuel and DraftKings? And which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, all from a DFS expert who won a prestigious Millionaire Maker tournament!