NFL Wild Card Weekend 2025 will conclude on Monday Night Football when the Los Angeles Rams host the Minnesota Vikings at 8 p.m. ET. Wildfires in Southern California have moved the game to State Farm Stadium in Glendale, Arizona. The Vikings are 2.5-point favorites despite losing to the Rams on the road earlier this season. How will the rematch unfold, and who are the best options in the NFL DFS player pool for Monday Night Football?

Before making any Rams vs. Vikings NFL DFS picks on sites like DraftKings and FanDuel, you need to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with SportsLine members. 

His methodology has led to enormous cashes on FanDuel and DraftKings. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him could be way up.

Now, McClure has turned his attention to Monday's Wild Card Weekend in the 2025 NFL playoffs and locked in his top daily Fantasy football picks. 

We can tell you one of McClure's top NFL DFS picks for Monday Night Football is Rams running back Kyren Williams. He's also targeting Vikings quarterback Sam Darnold, who has had multiple passing touchdowns in 12 of his 17 starts this season, including a couple of touchdowns against the Rams earlier this year.

McClure is also targeting a player who could go off for MASSIVE numbers on Monday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You ABSOLUTELY NEED to see who they are before locking in any lineups.

What are the top NFL DFS picks for Wild Card Weekend on Monday Night Football, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!