There's a two-game NFL DFS slate on Saturday with Steelers vs. Bengals at 4:30 p.m. ET and Bills vs. Chargers at 8 p.m. ET. Big names like Josh Allen, Stefon Diggs, Austin Ekeler and Najee Harris could factor into Saturday NFL DFS lineups, but you also have to be mindful to balance out your lineups with low-priced alternatives. Perhaps you could consider Bengals RB Chase Brown for your daily Fantasy football strategy since he's produced at least 51 scrimmage yards in three straight games. How should you approach Steelers players with Mason Rudolph under center? Before making your Saturday Week 16 NFL DFS picks on sites like DraftKings and FanDuel, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once. This season, McClure has won two showdown tournaments and posted a 36x ROI on a recent Monday Night Football slate. A SportsLine subscriber also won $100,000 in December using McClure's NFL DFS player pool. Anyone who has followed him is way up.

Now, McClure has turned his attention to the Week 16 Saturday NFL DFS slate and locked in his top daily Fantasy football picks.

We can tell you one of McClure's top Saturday NFL DFS picks for Week 16 is Bills running back James Cook at $6,900 on DraftKings and $8,500 on FanDuel. Part of McClure's optimal NFL DFS strategy also includes rostering Chargers receiver Quentin Johnston at $4,000 on DraftKings and $5,600 on FanDuel. The first-round pick out of TCU is coming off back-to-back solid showings as he had a career-high of 91 yards two weeks ago and followed that up by scoring his second career touchdown last week.

McClure is also targeting a player who could go off for MASSIVE numbers on Saturday! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks for Saturday, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!