MLB Opening Day 2025 is finally here, and there are 14 games on the MLB schedule for Thursday, including Juan Soto making his New York Mets debut as they take on the Houston Astros. Mets vs. Astros is set to get underway from Daikin Park at 4:10 p.m. ET. Before setting your MLB DFS lineups on daily Fantasy sites like DraftKings and FanDuel for 2025 MLB Opening Day, you NEED to see the top MLB DFS picks from Mike McClure. McClure is a daily Fantasy pro with nearly $2 million in career winnings. 

When it comes to MLB, McClure is at his best. Recognized in the book "Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune," McClure's proprietary MLB DFS projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.

One of McClure's top MLB DFS picks for MLB Opening Day 2025 is Phillies first baseman Bryce Harper at $5,100 on DraftKings and $4,000 on FanDuel for MLB DFS lineups. McClure is also rostering Angels catcher Logan O'Hoppe ($2,900 on DraftKings and $2,800 on FanDuel). The slugging 25-year-old catcher has hit 34 home runs over 675 at-bats the last two seasons 

McClure is also targeting a player who is set to EXPLODE for huge numbers on 2025 MLB Opening Day! The stars are aligning for him to return tournament-winning value, and he comes at a price that won't break the bank. This pick could be the difference between cashing in big or going home with nothing!

What players can you bank on in MLB DFS for MLB Opening Day 2025, and which undervalued player is a MUST-ROSTER?... Join SportsLine now to see DFS pro Mike McClure's top picks and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!