The No. 3 seed Los Angeles Lakers are set to host the No. 6 seed Minnesota Timberwolves for Game 2 of their first round Western Conference playoff series. The Timberwolves won Game 1 in dominant fashion, beating the Lakers 117-95. Anthony Edwards had 22 points, nine assists, and eight rebounds in the win. These teams met four times during the regular season in which the home team won all four matchups.

Tipoff from the Crypto.com Arena in Los Angeles is set for 10 p.m. ET. The Lakers were 31-10 at home during the regular season, which was the third-best record in the league. Los Angeles is a 5.5-point favorite in the latest Timberwolves vs. Lakers odds from SportsLine consensus, while the over/under for total points is 210.5. L.A. is at -251 on the money line (risk $251 to win $100), while Minnesota is at +205 (risk $100 to win $205). Before making any Lakers vs. Timberwolves picks, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the first full week of the 2025 NBA playoffs on a sizzling 156-116 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It is also 22-11 (67%) on top-rated NBA against-the-spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Timberwolves vs. Lakers 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in almost 60% of simulations!

Who wins Timberwolves vs. Lakers, and which side of the spread hits in almost 60% of simulations? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 156-116 roll on top-rated NBA picks!