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Cowboys vs. Giants betting preview: Odds, picks, props, trends, injuries, weather and more for Week 4 Thursday Night Football

Before you lock in your plays for Thursday's Dallas at New York Giants NFL game, check out our full betting preview.

The past two Thursday Night Football games have featured blowouts from the AFC East. Perhaps the NFC East will fare better in terms of a competitive game as the Dallas Cowboys (1-2) visit the New York Giants (1-2) tonight to kick off Week 4, with the loser claiming sole ownership of the divisional basement. The Giants haven't beaten Dak Prescott since his 2016 rookie season, and the Cowboys are 5.5-point favorites with a total of 45.5. There come be some rain in East Rutherford, N.J. 

It's the first of seven scheduled standalone games for the mega-popular Cowboys, and if they lose the seat of head coach Mike McCarthy is going to get scorching hot. Dallas had won 16 straight regular-season home games before being dominated at JerryWorld the past two Sundays, which has shot McCarthy up to a +450 second favorite to be the first NFL coach fired after Jacksonville's Doug Pederson (+150). 

Prescott, meanwhile, lost both matchups to the Giants in his first year but has won 12 in a row since, throwing for a combined 26 touchdowns and only six interceptions. He even had a receiving touchdown in a 37-34 victory in 2020. Only three quarterbacks in NFL history have won more consecutive games against a single opponent than Prescott has vs. New York: Bob Griese won 17 straight against the Bills; Tom Brady had a 13-game run against the Bills; and Steve Young won 13 in a row vs. the Rams.

The Giants' Brian Daboll was the betting favorite to be the first NFL coach fired after two weeks but is now third on the board at +800 following New York's surprising win in Cleveland this past Sunday. The Giants try to win on a Thursday for the first time since 2015 and pull off the Sunday-Thursday sweep for the first time since 2014.

We'll take you through every aspect of the Cowboys-Giants game that you need to know before you lock in your bets, including SportsLine expert picks, props, trends, DFS, injury information and everything else that will help you know which plays are worth making for the primetime matchup.

Who wins Cowboys vs. Giants in the Week 4 Thursday night game, and what critical X-factor makes one side of the spread hit HARD? Join SportsLine right now to see everything you need to know about the game in the Thursday night matchup to kick off Week 4 of the 2024 season!!

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Matt Severance
Matt SeveranceSeverance Pays

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