Deion Sanders and the Colorado Buffaloes (1-0) hit the road to take on the Nebraska Cornhuskers (1-0) on Saturday in one of college football's fiercest rivalry games. Kickoff at Memorial Stadium in Lincoln, Neb. is scheduled for 7:30 p.m. ET. The Buffs are coming off a 31-26 win over FCS powerhouse North Dakota State. Heisman Trophy candidates Travis Hunter and Shedeur Sanders were both outstanding for the Buffs in the win. The Huskers are coming off a 40-7 blowout win over UTEP in Week 1. Highly touted freshman quarterback Dylan Raiola was sharp in his college debut. 

The Huskers are 6.5-point favorites in the latest Nebraska vs. Colorado odds via SportsLine consensus, while the over/under for total points scored is 55.5. Nebraska is a -243 (risk $243 to win $100) favorite on the money line, with Colorado listed as a +196 underdog (see up-to-date odds for every game this week on our college football odds page). 

Before you make any Colorado vs. Nebraska picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is a NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor destroyed the books in college football in 2023, netting a whopping 57.9 units while posting a 107-45-2 record. Anyone who followed his picks finished the season WAY UP!

Now, Kaylor has locked in a confident against-the-spread pick for Colorado vs. Nebraska in their Week 2 matchup. We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Colorado vs. Nebraska in their Week 2 matchup in Lincoln, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who went 107-45-2, returning $5,790 for $100 bettors, betting on college football in 2023, and find out!