The popularity of the NCAA Tournament over the years has been built on upsets, buzzer beaters and one word… Cinderella. 

There is nothing like picking a No. 13 seed to make the Sweet 16 or betting the money line on a No. 12 seed in the first round and being right. Two years ago, we saw a tournament dominated by Cinderellas when lower seeds Miami, San Diego State and Florida Atlantic all made the Final Four. Last year we didn't see a ton of upsets but Cinderella struck again with No. 11 seed NC State reaching the Final Four. 

Identifying the right Cinderella can be profitable for sports bettors as well. A lot of people like to bet on a team to win the National Championship, although wagering on a lower seed to make the Final Four is another way to make a profit. 

Here are teams in each region that have the ingredients to make a surprise run in the NCAA Tournament and be this year's Cinderella. 

Which teams have what it takes to make a Cinderella run into the Final Four? And which No. 11 seed could make a deep run? Join SportsLine right now to see the top Cinderella picks from each region, all from the expert who is on a 57-32 ATS run at SportsLine!