The PGA Tour's best golfers return to Arnold Palmer's Bay Hill Club & Lodge for the 2025 Arnold Palmer Invitational beginning on Thursday, March 6. Scottie Scheffler, the defending champion and a two-time winner of this event, enters this week's tournament as the +320 favorite (risk $100 to win $320), according to the latest 2025 Arnold Palmer Invitational odds. The No. 1 ranked player in the world is followed by Rory McIlroy (+750), Ludvig Aberg (+1600) and Xander Schauffele (+1600) on the PGA odds board. 

The 2025 Arnold Palmer Invitational field also features major champions like Collin Morikawa (+2200), Hideki Matsuyama (+2500), Justin Thomas (+2800) and Keegan Bradley (+5500). Matsuyama is +190 (risk $100 to win $190) to finish inside the top 10, while Bradley is +750 (risk $100 to win $750) to crack the top five. The 2025 Arnold Palmer Invitational first-round tee times begin on Thursday at 7:40 a.m. ET.

Before locking in your 2025 Arnold Palmer Invitational picks, you NEED to see the golf predictions and projected leaderboard from the proven computer model at SportsLine, considering its MASTERY of calling golf tournament. In fact, it's nailed 13 majors, three last year alone, and three straight Masters!

One major surprise the model is calling for at the Arnold Palmer Invitational 2025: Rory McIlroy, a 27-time PGA Tour champion and one of the top favorites, stumbles this week and barely cracks the top five. Another surprise: Patrick Cantlay, a 30-1 longshot, makes a strong run at the title. He's a target for anyone looking for a HUGE payday! Cantlay is coming off a T-5 finish at the Genesis Invitational and is ranked second in birdie average (5.56), second in greens in regulation percentage (76.39%) and sixth in putting average (1.655). 

Also, the model is targeting TWO OTHER golfers with odds of 30-1 or longer who will make a strong run at the title! Anyone who backs these golfers could hit it BIG. You ABSOLUTELY NEED to see who they are before locking in any 2025 Arnold Palmer Invitational picks!

So who wins the 2025 Arnold Palmer Invitational, and which HUGE longshots make a serious run? ... Join SportsLine to see who you can bank on to win BIG, and see which longshots make a run at the title, all from the model that's nailed 13 majors, including three straight Masters!