11:00 pm UTC
UTA @ IND -16
San Francisco
Denver
San Francisco
| PASSING | CP/ATT | YD | TD | INT | FUML | FP | |
| J. Garoppolo | Jimmy Garoppolo | 19/30 | 239 | 1.30 | 1.00 | 0.12 | 16.51 |
| RUSHING | RUSH | YD | TD | YPC | FUML | FP | |
| J. Wilson | Jeff Wilson | 17.9 | 72 | 0.36 | 4.0 | 0.20 | 10.78 |
| D. Samuel | Deebo Samuel | 6.2 | 41 | 0.39 | 6.7 | 0.17 | 14.58 |
| J. Mason | Jordan Mason | 5.7 | 26 | 0.15 | 4.6 | 0.08 | 4.34 |
| RECEIVING | REC | YD | TD | YPR | FUML | FP | |
| D. Samuel | Deebo Samuel | 4.2 | 67 | 0.27 | 15.9 | 0.17 | 14.58 |
| B. Aiyuk | Brandon Aiyuk | 4.2 | 62 | 0.26 | 14.7 | 0.05 | 8.04 |
| G. Kittle | George Kittle | 4.2 | 56 | 0.29 | 13.4 | 0.05 | 7.53 |
| J. Jennings | Jauan Jennings | 2.2 | 26 | 0.22 | 11.6 | 0.02 | 3.88 |
| R. Dwelley | Ross Dwelley | 1.0 | 18 | 0.29 | 18.4 | 0.01 | 3.63 |
| K. Juszczyk | Kyle Juszczyk | 1.4 | 15 | 0.09 | 10.5 | 0.02 | 2.93 |
| DEF-ST | SACK | INT | FREC | FP | PA | Defensive TDs | |
| S. DST | SF DST | 3.02 | 0.54 | 0.9 | 10.35 | 19 | 0.13 |
PLAYERS LISTED AS OUT OR DOUBTFUL:Trey Lance, Elijah Mitchell, Tyler Kroft, Tyrion Davis-Price, Jordan Matthews, Jimmie Ward, Jason Verrett, Azeez Al-Shaair, Arik Armstead, Maurice Hurst, Curtis Robinson, Kalia Davis *Questionable players are included in the projection. | |||||||
San Francisco players
| PASSING |
| Jimmy Garoppolo |
| RUSHING |
| Jeff Wilson |
| Deebo Samuel |
| Jordan Mason |
| RECEIVING |
| Deebo Samuel |
| Brandon Aiyuk |
| George Kittle |
| Jauan Jennings |
| Ross Dwelley |
| Kyle Juszczyk |
| DEF-ST |
| SF DST |
| CP/ATT | YD | TD | INT | FUML | FP |
| 19/30 | 239 | 1.30 | 1.00 | 0.12 | 16.51 |
| RUSH | YD | TD | YPC | FUML | FP |
| 17.9 | 72 | 0.36 | 4.0 | 0.20 | 10.78 |
| 6.2 | 41 | 0.39 | 6.7 | 0.17 | 14.58 |
| 5.7 | 26 | 0.15 | 4.6 | 0.08 | 4.34 |
| REC | YD | TD | YPR | FUML | FP |
| 4.2 | 67 | 0.27 | 15.9 | 0.17 | 14.58 |
| 4.2 | 62 | 0.26 | 14.7 | 0.05 | 8.04 |
| 4.2 | 56 | 0.29 | 13.4 | 0.05 | 7.53 |
| 2.2 | 26 | 0.22 | 11.6 | 0.02 | 3.88 |
| 1.0 | 18 | 0.29 | 18.4 | 0.01 | 3.63 |
| 1.4 | 15 | 0.09 | 10.5 | 0.02 | 2.93 |
| SACK | INT | FREC | FP | PA | Defensive TDs |
| 3.02 | 0.54 | 0.9 | 10.35 | 19 | 0.13 |
PLAYERS LISTED AS OUT OR DOUBTFUL:
Trey Lance, Elijah Mitchell, Tyler Kroft, Tyrion Davis-Price, Jordan Matthews, Jimmie Ward, Jason Verrett, Azeez Al-Shaair, Arik Armstead, Maurice Hurst, Curtis Robinson, Kalia Davis
*Questionable players are included in the projection.