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Yankees vs. Diamondbacks line, odds, start time, pick, best bets for April 1 matchup from proven model

SportsLine's projection model, which is on a profitable 34-18 run, has locked in its MLB picks for Arizona Diamondbacks vs. New York Yankees at Yankee Stadium on Tuesday

By@SportsLineUpdated: Apr 01, 2025 9:56PM UTC . 2 min read

The New York Yankees hope their "Torpedo" bats can generate the same results as they did against the Brewers over the weekend as they welcome the Arizona Diamondbacks for the beginning of a three-game series Tuesday. The Yankees (3-0), who reached the World Series following a 94-68 regular season last year, outscored the Brewers 36-14 in their sweep. The Diamondbacks (2-2) split a four-game series with the Chicago Cubs. Arizona went 89-73 last season and missed the postseason via a tiebreaker. 

First pitch from Yankee Stadium in the Bronx is set for 7:05 p.m. ET. Arizona is a -118 favorite on the money line (risk $118 to win $100) in the latest Yankees vs. Diamondbacks odds, while New York is a -101 underdog. The over/under is 8.5 in the latest MLB odds via SportsLine consensus.

Before making any Diamondbacks vs. Yankees picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 2 of the 2025 MLB season on a 34-18 roll on top-rated run-line picks (+729). Anybody following could have seen strong returns!

The model has simulated Yankees vs. Diamondbacks 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line is the better value!

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