The Texas Longhorns (19-15) and the Xavier Musketeers (21-11) are set to play in a First Four battle on Wednesday. The winner of this matchup secures the No. 11 seed in the Midwest and will move on to play No. 6 seed Illinois on Friday. Both teams have gone 3-2 ATS in their last five matchups.

Tip-off from the University of Dayton Arena in Dayton, Ohio, is set for 9:10 p.m. ET. Xavier is a 2.5-point favorite in the latest Xavier vs. Texas odds from SportsLine consensus, while the over/under for total points scored is 149.5.

Before making any Xavier vs. Texas picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Xavier vs. Texas 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread cashes in well over 60% of simulations!

So who wins Xavier vs. Texas, and which side of the spread cashes in well over 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!