The No. 6 Houston Cougars will put their perfect record on the line when they face the Xavier Musketeers in Cincinnati. Tipoff is set for 6:30 p.m. ET on Friday at Cintas Center. Houston is favored by 8.5 points in the latest Xavier vs. Houston odds, while the over/under is set at 138.5 points, per SportsLine consensus. 

Before entering any Houston vs. Xavier picks, you NEED to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 4 of the 2023-24 season on an 94-61 roll on all top-rated college basketball picks dating back to last season, returning more than $1,800 for $100 players. It is also off to an 8-2 roll on top-rated spread picks this season. Anyone following has seen HUGE returns!

The model has simulated Xavier vs. Houston 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Xavier vs. Houston? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!