A 2022 Big East Tournament battle is on tap between the Xavier Musketeers and the Butler Bulldogs at 4:30 p.m. ET on Wednesday at Madison Square Garden. Butler is 13-18 while Xavier is 18-12. The Musketeers are ranked seventh in the Big East; Butler is ranked ninth. 

The Musketeers are favored by 5.5 points in the latest Xavier vs. Butler odds from Caesars Sportsbook, while the over-under is set at 131. Before you make any Butler vs. Xavier picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Xavier vs. Butler 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Xavier vs. Butler? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.