The Cleveland Guardians (5-6) and the Chicago White Sox (2-9) play in a divisional matinee on Thursday. The Guardians are going for the three-game sweep. On Tuesday, Cleveland beat the White Sox 3-2. Jonathan Cannon (0-1, 3.12 ERA) is on the hill for Chicago. Gavin Williams (0-0, 4.50 ERA) gets the start for Cleveland.

First pitch is scheduled for 1:10 p.m. ET at Progressive Field in Cleveland, Ohio. The Guardians are the -253 money-line favorites (bet $253 to win $100) in the latest White Sox vs. Guardians odds, while the White Sox are +205 underdogs (bet $100 to win $205). The over/under for total runs scored is 7 in the latest MLB odds via SportsLine consensus. 

Before you make any White Sox vs. Guardians picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

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The model has simulated White Sox vs. Guardians 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has ALL the value!

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