The Chicago White Sox and Cleveland Guardians are set to begin a three-game series in Cleveland Tuesday, with the Guardians off to a 3-5 start and the White Sox at 2-7 through nine games. Cleveland is coming off a 6-2 loss to the Angels Sunday, losing two of three games in the series. Chicago enters off a 4-3 loss to the Tigers Sunday in a three-game sweep.

First pitch from Progressive Field in Cleveland, Ohio., is set for 4:10 p.m. ET. Cleveland is a -196 favorite on the money line (risk $196 to win $100) in the latest White Sox vs. Guardians odds, while Chicago is a +163 underdog. The over/under is 7.5 in the latest MLB odds via SportsLine consensus.

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