The Virginia Cavaliers (2-0) and the Villanova Wildcats (2-2) link up in the 2024 Hall of Fame Series on Friday afternoon. The Cavaliers are on a two-game win streak to open the season, topping Coppin State 62-45 on Nov. 11. As for the Wildcats, they fell to Saint Joseph's 83-76 on Tuesday. 

Tipoff is set for 5 p.m. ET on Friday at CFG Bank Arena in Baltimore, MD. The Wildcats are favored by 4.5 points in the latest Virginia vs. Villanova odds, while the over/under is 129.5 points per SportsLine consensus. Before entering any Virginia vs. Villanova picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 2 of the 2024-25 season on a 155-110 roll (+2102) on all top-rated college basketball picks dating back to 2023. Anyone following has seen HUGE returns!

The model has simulated Virginia vs. Villanova 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in over 60% of simulations!

So who wins Virginia vs. Villanova, and which side of the spread hits in over 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!