The Villanova Wildcats look to get back into the win column when they take on the Xavier Musketeers in a key Big East Conference matchup on Tuesday. Villanova dropped an 80-68 contest at St. John's on Saturday, while Xavier downed DePaul 77-63 that same day. The Wildcats (11-6, 4-2 Big East), who are fourth in the conference, have won three of their past four games. The Musketeers (10-7, 2-4 Big East), who are eighth in the Big East, have lost five of seven.

Tipoff from Cintas Center in Cincinnati is set for 6:30 p.m. ET. Villanova leads the all-time series 34-8, but the teams have split the last four meetings. Xavier is a 2.5-point favorite in the latest Villanova vs. Xavier odds from SportsLine consensus, while the over/under for total points scored is 145.5.

Before entering any Villanova vs. Xavier picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 11 of the 2024-25 season on a 195-134 roll (+2882) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Villanova vs. Xavier 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread is the better value!

So who wins Villanova vs. Xavier, and which side of the spread is the better value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!