An SEC showdown has the Vanderbilt Commodores (17-8) and the No. 17 Kentucky Wildcats (17-8) battling on Wednesday. The Commodores have dropped two straight games. On Feb. 15, Tennessee topped Vanderbilt 81-76. Kentucky is also coming off a loss. The Wildcats fell to Texas 82-78 on Saturday. Lamont Butler, Jaxon Robinson and Kerr Kriisa are all out for Kentucky. 

Tipoff is scheduled for 7 p.m. ET at Rupp Arena at Central Bank Center in Lexington, Ky. The Wildcats are 4.5-point favorites in the latest Vanderbilt vs. Kentucky odds from SportsLine consensus, while the over/under for total points scored is 162.5. The Wildcats are -217 (risk $217 to win $100) money-line favorites. 

Before entering any Vanderbilt vs. Kentucky picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 16 of the 2024-25 season on a 213-158 roll (+1675) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Vanderbilt vs. Kentucky 10,000 times and the results are in. The model is leaning Under, and it also says one side of the spread hits in 70% of simulations!

So who wins Vanderbilt vs. Kentucky, and which side of the spread hits in 70% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 213-158 on top-rated college basketball picks!