Ranked heavyweights will meet in the main event of UFC Fight Night on Saturday as No. 12-ranked Derrick Lewis takes on No. 15-ranked Rodrigo Nascimento. The main UFC fight card is set for 7 p.m. ET from the Enterprise Center in St. Louis. Lewis is a -145 favorite (risk $145 to win $100), while Nascimento is priced at +125 (risk $100 to win $125) in the latest UFC Fight Night: Lewis vs. Nascimento odds. Before making any UFC Fight Night picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani.

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In the last 11 UFC pay-per-view events, Vithlani has gone 7-4 on main-event picks and his main-card selections in that span have netted his followers a profit of more than $1,200. 

His highlights include calling an upset for Sean O'Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him is WAY UP!

This week at UFC Fight Night: Lewis vs. Nascimento, we can tell you Vithlani is backing Sean Woodson (-195) to get his hand raised against Alex Caceres (+165) in a showdown of featherweight prospects on the main card. "Caceres is a veteran featherweight with explosive striking and dangerous submissions. However, Caceres has faltered against higher-caliber opponents. Woodson is a smart fighter who stays defensively sound and knows how to score points," Vithlani told SportsLine.

Vithlani has strong picks for Lewis vs. Nascimento and other bouts on the UFC Fight Night card. He's also backing a fighter who "has a ton of experience against a wide variety of styles" to emerge with a dominant victory! You ABSOLUTELY need to see his UFC Fight Night picks before making any of your own!

Who wins Lewis vs. Nascimento and which fighter is a MUST-BACK? Join SportsLine now to see which fighters you need to be all over Saturday, all from the expert  who profited more than $1,500 in UFC pay-per-view cards!