Featherweight champion Alexander Volkanovski will make the second defense of his title on Saturday against top-ranked contender Brian Ortega in the main event of UFC 266. The main UFC 266 fight card is set for 10 p.m. ET from the T-Mobile Arena in Las Vegas.

Volkanovski (22-1) is 9-0 in the UFC, and his meteoric rise included taking the title from popular former champion Max Holloway, who he also defeated in a razor-thin rematch in his first title defense last July. Ortega (15-1-1) is a well-rounded prospect who saw his own climb up the rankings hampered by injuries and a lopsided loss to Holloway three years ago in his first UFC title bid. 

Volkanovski is a -155 favorite (risk $155 to win $100), while Ortega is a +135 underdog (risk $100 to win $135) in the latest UFC 266 odds from Caesars Sportsbook. Before making any picks of your own for Volkanovski vs. Ortega and the rest of the UFC 266 card, make sure you check out the MMA predictions from SportsLine MMA expert Andrew Gombas.  

Gombas is a former NCAA wrestler who taps into his experience on the mat to help understand and dissect the X's and O's of MMA matchups in a manner that sets him apart from other MMA analysts. He started the MMA handicapping service MMA Knockout Bets in 2018 and has shown a profit every year since.

With more than 1,200 selections tracked by the third-party monitoring service Bet MMA, he has shown a 10 percent return on investment for his followers. In 2020, $100 bettors who tailed his picks were up $9,200. Among his recent memorable selections was calling the upset by Brandon Moreno (+200) against Deiveson Figueiredo (-240) for the flyweight title at UFC 263 in June. Anyone who has followed him is WAY UP! 

Now, he has locked in on UFC 266 from every angle and released his top selections. A successful parlay of these picks would result in a payout of 9-1! 

For UFC 266, we can tell you Gombas is taking Robbie Lawler (-150) to get his hand raised against Nick Diaz (+130) in a much-anticipated middleweight battle.

Gombas has locked in strong picks for Volkanovski vs. Ortega and every other bout on the UFC 266 card. He's also backing one fighter to prevail "in a complete mismatch!" You ABSOLUTELY need to see his picks before locking in any UFC Fight Night bets of your own.

Who wins Volkanovski vs. Ortega? And which fighter is a MUST-BACK? ... Join SportsLine right now to see which fighters you need to be all over at UFC 266, all from the MMA insider who returned nearly $9,200 last year!