Israel Adesanya takes on Jan Blachowicz in the last of three title fights to headline the UFC 259 card Saturday in Las Vegas. The main UFC 259 fight card is set for 10 p.m. ET. Adesanya, the current middleweight champion, is fighting for the light heavyweight crown against Blachowicz, who is the sitting champion. Adesanya is a -240 favorite (risk $240 to win $100), while Blachowicz is a +200 underdog (risk $100 to win $200) in the latest Blachowicz vs. Adesanya odds at William Hill Sportsbook.

Before making any UFC 259, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley. Over the past 25 months, $100 bettors who have followed Marley's picks are up more than $21,000. The accomplished MMA analyst has seen memorable run in 2020 carry over into 2021. He has now nailed 28 of his last 39 UFC main-event picks, a stretch that included a streak of five consecutive underdogs!

At UFC Fight Night last weekend, Marley's winners included telling SportsLine members to expect a dominant performance from Ciryl Gane (-265) against Jairzinho Rozenstruik (+225) in the heavyweight main event. Gane earned a lopsided decision to give Marley's followers an easy winner. Anyone who has followed Marley is WAY UP! 

This week at UFC 259, we can tell you Marley is backing Islam Makhachev (-345) to get a decision victory over Drew Dober (+285) in a battle of lightweight prospects. He's also backing one fighter who "pushes at a higher pace" to score a shocking upset! You ABSOLUTELY need to see Marley's picks before making any of your own.

Who wins Blachowicz vs. Adesanya and every bout on the UFC 259 card? And which underdog is a MUST-BACK? ... Join SportsLine right now to see which fighters you need to be all over Saturday, all from the expert who's up more than $21,000 on MMA picks and has nailed a whopping 28 of the last 39 main events!