The ninth-ranked Connecticut Huskies look to win their ninth consecutive game when they battle the Villanova Wildcats in a key Big East Conference matchup on Wednesday. UConn is coming off an 87-84 win over Providence on Sunday, while Villanova cruised to a 100-56 win over DePaul on Saturday. The Huskies (12-3, 4-0 Big East), the two-time defending national champions, are 3-0 on the road this season. The Wildcats (10-5, 3-1 Big East), who are 8-1 on their home court, are 1-0 against ranked opponents in 2024-25.

Tip-off from Finneran Pavilion in Villanova, Pa., is set for 6:30 p.m. ET. Villanova is a 1.5-point favorite in the latest UConn vs. Villanova odds from SportsLine consensus, while the over/under for total points scored is 145.

Before making any UConn vs. Villanova picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 10 of the 2024-25 season on a 189-130 roll (+2985) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen huge returns.

The model has simulated UConn vs. Villanova 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting 70% of the time!

So who wins UConn vs. Villanova, and which side of the spread hits 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!