We've got another exciting Northwest Division matchup on the Wednesday NBA schedule as the Portland Trail Blazers hit the road to take on the Denver Nuggets at Ball Arena. Denver is 35-19 overall and 18-8 at home, while Portland is 23-31 overall and 8-18 on the road. These teams also played on Monday with Denver winning 146-117. The Nuggets have now won seven straight games.  Aaron Gordon (calf), Jamal Murray (knee), and Michael Porter Jr. (hamstring) are all listed as game-time decisions for the Nuggets. 

Tipoff in Denver is at 9 p.m. ET. The Nuggets are favored by 11.5 points in the latest Nuggets vs. Trail Blazers odds via SportsLine consensus, and the over/under is 232.5 points. Before locking in any Nuggets vs. Trail Blazers picks, you'll want to see the NBA predictions and betting advice from the proven computer simulation model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 16 of the 2024-25 NBA season on a sizzling 144-102 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Nuggets vs. Trail Blazers 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that hits in 70% of computer simulations. You can only see the model's pick at SportsLine.

So who wins Nuggets vs. Trail Blazers? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.