The Detroit Tigers and Cleveland Guardians open their best-of-five American League Division Series on Saturday. Sixth-seeded Detroit swept Houston in their Wild Card series, while second-seeded Cleveland will be in action for the first time this postseason after winning the AL Central title.

First pitch is scheduled for 1:08 p.m. ET from Progressive Field in Cleveland. The Guardians are the -143 money-line favorites (risk $143 to win $100) in the latest Tigers vs. Guardians odds, while the Tigers are +121 underdogs. The over/under for total runs scored is 6.5 in the latest MLB odds via SportsLine consensus. 

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The model has simulated Tigers vs. Guardians 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

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