Thursday Night Football Cowboys vs. Saints game line, odds: Proven model reveals NFL picks, predictions for TNF

The Dallas Cowboys (7-4) and New Orleans Saints (5-6) will face off in the Week 13 edition of Thursday Night Football. Dallas is on a two-game losing streak and lost to the Las Vegas Raiders on Thanksgiving. New Orleans is also on a losing streak, dropping four straight. Dallas head coach Mike McCarthy has tested positive for COVID-19 and is out for this matchup. 

Kickoff from Caesars Superdome is set for 8:20 p.m. ET. Dallas is favored by six points in the latest Cowboys vs. Saints odds from Caesars Sportsbook, while the Over-Under is 46. Before making you make any Cowboys vs. Saints picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,100 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 13 of the 2021 season on an incredible 131-94 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model knows Dallas quarterback Dak Prescott is eighth in the NFL in passing yards (2,932) and tied for eighth in passing touchdowns (22). Despite falling short to Las Vegas, Prescott went 32-of-47 for 375 yards with two passing touchdowns. This was the fourth game this season in which Prescott threw for over 300 yards. 

The model also knows Saints linebacker Damario Davis is the leading tackler for New Orleans. He has recorded 76 total tackles, including 51 solo. Davis also leads the team with 11 tackles for loss while swatting away four passes. The Arkansas State product has three games with double-digit tackles. Against Buffalo, he logged 10 total tackles. 

Now, the model has set its sights on Cowboys vs. Saints on Thursday Night Football. We can tell you it's leaning Over the total, and it also says one side of the spread hits in nearly 60 percent of simulations! You ABSOLUTELY need to see it before locking in any Cowboys vs. Saints picks of your own.

So who wins Cowboys vs. Saints on Thursday Night Football? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to see which side of the Cowboys vs. Saints spread to back, all from the dialed-in NFL model that's up almost $7,500 on top-rated picks!

Simulations for Cowboys vs. Saints run every 15 minutes until kickoff and are subject to change. SportsLine members can always get the latest projections on the game forecast page.

Dallas Cowboys at New Orleans Saints | 12/02 | 8:20 P.M. ET 

Against The Spread 

Pick: New Orleans +6
The Saints cover in 58 percent of simulations

Over-Under

Pick: Over 46
The Over hits in 50 percent of simulations

Money line

Pick: New Orleans +220
The Saints win in 42 percent of simulations, bringing value at these odds 

Projected Final Score: Cowboys 25, Saints 22

Looking for the best picks against the spread, sharp plays on the total, and props you can take straight to the pay window? Join Jonathan Coachman on the Early Edge as he speaks with SportsLine's top handicappers to preview the day's biggest games. We promise to keep it short, sweet and to put some green in your pocket. Early Edge is in your feed every single day by 11 a.m. ET. Subscribe right here on YouTube to watch daily, plus don't miss the Early Edge specials and live shows!