The Houston Texans will try to dethrone the two-time defending Super Bowl champion Kansas City Chiefs when they meet in a Divisional Round matchup during the 2025 NFL playoffs on Saturday. Houston advanced with a 32-12 win over the Los Angeles Chargers during Wild Card weekend, while Kansas City is coming off a bye. The Texans (10-7), who won the AFC South, are 5-4 on the road this season. The Chiefs (15-2), who won their ninth consecutive AFC West crown, are 8-0 on their home field.

Kickoff from GEHA Field at Arrowhead Stadium is set for 4:30 p.m. ET. The Chiefs are 8-point favorites in the latest Texans vs. Chiefs odds, while the over/under for total points scored is 42. The Chiefs are -457 money-line favorites (risk $457 to win $100), while the Texans are +353 underdogs (risk $100 to win $353). Before entering any Texans vs. Chiefs picks, you NEED to see the NFL playoff predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the Divisional Round of the 2025 NFL playoffs on a 31-15 betting hot streak on top-rated NFL picks this year -- a stunning 67% success rate. Longer term, it is on a 211-143 roll on top-rated NFL picks that dates back to the 2017 season and a 65-36 roll on top-rated NFL picks since Week 7 of 2022.

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The model has simulated Texans vs. Chiefs 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits in over 50% of simulations!

So who wins Texans vs. Chiefs on Saturday in the NFL playoffs 2025? And which side of the spread cashes in over 50% of simulations? ... Join SportsLine RIGHT NOW to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks!