An intriguing Group of Five versus Power Four battle will take place on Saturday in the 2024 New Mexico Bowl as Louisiana takes on TCU. The Ragin' Cajuns are 10-3 and are coming off a defeat in the Sun Belt Championship Game, while the Horned Frogs (8-4) have won their last three games. This will be the first-ever meeting between these programs, and this is also the first appearances by either a Sun Belt or a Big 12 team in the New Mexico Bowl.

Kickoff is set for 2:15 p.m. ET at University Stadium in Albuquerque, N.M. The Horned Frogs are favored by 9.5 points in the latest Louisiana vs. TCU odds, while the over/under is 60.5 points, per SportsLine consensus. 

Before entering any TCU vs. Louisiana picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it went a profitable 43-35 on top-rated picks during the 2024 season. It also nailed all four winners in the first round of the College Football Playoff! Anyone following has seen impressive returns!

The model has simulated Louisiana vs. TCU 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations!

So who wins TCU vs. Louisiana, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!