The Stanford Cardinal will play the program's first ACC conference game when they face the Syracuse Orange on Friday at the JMA Wireless Dome in Syracuse, N.Y. The Cardinal joined the conference this season after being longtime members of the Pac-12. Both Stanford (1-1) and Syracuse (2-0) are coming off open weeks. Two weeks ago, the Cardinal beat Cal Poly, while the Orange upset No. 23 Georgia Tech.

Kickoff is 7:30 p.m. ET. The Orange are 8.5-point favorites in the latest Syracuse vs. Stanford odds, while the over/under for total points scored is 57.5. (See up-to-date odds for every game this week on our college football odds page.)

Before making any Stanford vs. Syracuse picks or college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.

The model knows that Syracuse has one of the most prolific passing attacks so far this season. Led by Ohio State transfer quarterback Kyle McCord, the Orange average 367.5 pass yards per game, which ranks third in the country, behind only Ole Miss and Miami. McCord ranks second in the nation in total offense (372.0 yards per game).

But the model also has taken into account that Stanford has done an excellent job this season in stopping the run. The Cardinal give up just 64.5 rushing yards per game, which leads the conference and ranks 12th in the country. In Stanford's victory over Cal Poly, the defense gave up just 25 rushing yards on 20 carries.

For Friday, the model has set its sights on Syracuse vs. Stanford. We can tell you it is leaning Under the total, and it also says one side of the spread hits in over 50% of simulations. You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Stanford vs. Syracuse? And which side of the spread hits in over 50% of simulations? ... Join SportsLine right now to find out which side of the Syracuse vs. Stanford spread you should be all over Friday, all from the model on a roll on college football picks.