Teams trending in opposite directions battle when the St. John's Red Storm face the Xavier Musketeers in a key Big East Conference matchup on Tuesday. St. John's is coming off a 70-62 win over Butler on Saturday, while Xavier dropped a 69-63 decision at Georgetown on Friday. The Red Storm (12-3, 3-1 Big East), who have won seven of their last eight games, are 1-1 on the road this season. The Musketeers (9-6, 1-3 Big East), who have lost five of their past seven games, are 8-1 on their home court.

Tip-off from Cintas Center in Cincinnati is set for 6:30 p.m. ET. St. John's is a 1.5-point favorite in the latest St. John's vs. Xavier odds from SportsLine consensus, while the over/under for total points scored is 153. 

Before making any St. John's vs. Xavier picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 10 of the 2024-25 season on a 189-130 roll (+2985) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen huge returns.

The model has simulated St. John's vs. Xavier 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60% of simulations!

So who wins St. John's vs. Xavier, and which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!