The San Antonio Spurs will be without Victor Wembanyama for the remainder of the season, including their game against the Detroit Pistons in Austin on Friday night. San Antonio was able to overcome Wembanyama's absence on Thursday in its return from the All-Star break, notching a 120-109 win against Phoenix. Detroit is riding a four-game winning streak as it gets set for its first game in nine days. 

Tipoff is set for 8:30 p.m. ET on Friday at the Moody Center in Austin. The Pistons are favored by 4.5 points in the latest Spurs vs. Pistons odds, while the over/under is 233.5 points, per SportsLine consensus. Before entering any Pistons vs. Spurs picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the second half of the 2024-25 NBA season on a sizzling 147-104 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 18-9 (67%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns. 

The model has simulated Spurs vs. Pistons 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60% of simulations. You can only see the pick at SportsLine.

So who wins Spurs vs. Pistons? And which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.