No. 1 seed Gonzaga is a strong pick to come out of this region despite losses to Saint Mary's and Alabama. Michigan State falls to Davidson in the first round, even though the blue blood program beat 3-seeds Purdue and Wisconsin during the regular season. Alabama falls to a First Four winner, even though the Crimson Tide have already beaten Gonzaga and Baylor, both 1-seeds in the 2022 NCAA Tournament bracket.

Get every pick, every play, every upset and fill out the rest of your bracket with our help! ... Join SportsLine now to see which No. 2 seeds are a must-back, and which region features a 5-seed in the Elite Eight and a 14-seed delivering a first-round shocker, all from the model that has beaten 92% of bracket players two of the last three tournaments!