The No. 8 seed Southern Illinois Salukis will face the No. 9 seed Indiana State Sycamores in the first round of the 2025 Missouri Valley Conference Tournament on Thursday afternoon. Southern Illinois lost five of its final six games in the regular season, including a 95-77 setback at Indiana State on Sunday. The Sycamores had lost three consecutive contests prior to that victory.   

Tipoff is set for 1 p.m. ET on Thursday at the Enterprise Center in St. Louis. Southern Illinois is favored by 1.5 points in the latest Southern Illinois vs. Indiana State odds, while the over/under is 153.5 points, per SportsLine consensus. Before entering any Southern Illinois vs. Indiana State picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 18 of the 2024-25 season on a 221-162 roll (+1895) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Southern Illinois vs. Indiana State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins Southern Illinois vs. Indiana State? And which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.