An American Athletic battle is on tap between the South Florida Bulls and the Houston Cougars at noon ET on Saturday at TDECU Stadium. Houston is riding a two-game winning streak following victories at Memphis and Navy in its last two games. The Cougars are favored by 17.5 points in the latest South Florida vs. Houston odds from Caesars Sportsbook, while the over/under is set at 60. 

Before you make any Houston vs. South Florida picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated South Florida vs. Houston 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins South Florida vs. Houston? And which side of the spread is hitting well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.