Two division leaders in the NFC collide when the Philadelphia Eagles host the Seattle Seahawks on Monday Night Football. Kickoff is set for 8:15 p.m. ET. Seattle is a 6.5-point favorite in the latest odds from William Hill Sportsbook, while the Over-Under for total points scored is 49.

Before locking in any Eagles vs. Seahawks picks or NFL predictions, make sure you see what SportsLine's all-time No. 1 NFL expert, Mike Tierney, has to say. 

A national sportswriter whose work appears in The New York Times and Los Angeles Times, Tierney has covered the NFL for decades and reported from seven Super Bowls. He prefers to evaluate each game from the underdog's point of view and has used that philosophy to dominate the NFL, going 66-44 against the spread in 2019 and 63-46 in 2018. Tierney entered the 2020 season with a 282-222 record at SportsLine (2016-19) on all NFL picks, returning $3,704 to $100 players.

He also has had a sharp eye for the tendencies of the Seahawks, posting a stunning 16-7 record in his last 23 against-the-spread picks involving Seattle! Anyone who has followed him is WAY UP.

Now he's studied Seahawks vs. Eagles from every possible angle. We can tell you he's leaning Under the total, and he's also found a critical X-factor that has him jumping ALL OVER one side of the spread! You ABSOLUTELY need to see it before you lock in your own picks.

So who wins Seahawks vs. Eagles on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Eagles vs. Seahawks spread you should be all over, all from the expert who's 16-7 with his last 23 spread picks involving Seattle!