Monday Night Football features a matchup between the New Orleans Saints and Seattle Seahawks. Kickoff in Seattle is set for 8:15 p.m. ET. The Saints are favored by four points in the latest Saints vs. Seahawks odds from Caesars Sportsbook, while the over-under is 41.5.

Before you make any Saints vs. Seahawks picks or any other NFL predictions, you NEED to see which side SportsLine expert Larry Hartstein is on. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Entering the 2021 campaign, Hartstein was 351-291 all-time on NFL sides, returning more than $2,200 for $100 bettors. 

In addition, Hartstein has been on fire this season. He is a blistering 25-9 in his last 34 NFL picks, returning nearly $1,500 for $100 bettors! Anyone who has followed him is WAY UP.

New Orleans has strengths on both sides of the ball. Defensively, the Saints rank in the top five of the NFL in both scoring defense (18.2 points allowed per game) and turnover creation (two per game). Seattle's offense isn't the same without star quarterback Russell Wilson (finger), further bolstering the Saints' position in this matchup. On offense, QB Jameis Winston leads the NFL in touchdown percentage, with the Saints also landing inside the top 10 of the league in scoring 25.4 points per game.

Seattle is playing in front of the infamous "12th Man" at home, and the Seahawks have encouraging metrics to fall back on. Seattle ranks in the top 10 in both net yards per pass attempt (7.2) and yards per rush attempt (4.6), with the Seahawks posting a top-five red zone efficiency mark of 75 percent. Geno Smith has flashed competence at quarterback and can rely on one of the NFL's best wide receiver duos in Tyler Lockett and DK Metcalf.

Now, Hartstein has locked in another confident against the spread pick for Saints vs. Seahawks. We can tell you he's leaning under, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Saints vs. Seahawks on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Saints vs. Seahawks spread to jump on, all from the expert who's an outstanding 25-9 on NFL picks!