The No. 2 seed Alabama Crimson Tide and the No. 7 seed Saint Mary's Gaels play in the second round of the 2025 NCAA Tournament on Sunday evening. The Crimson Tide defeated Robert Morris 90-81 in the first-round tilt on Friday. In the meantime, Saint Mary's took down Vanderbilt 59-56 in their first-round contest. 

Tip-off from the Rocket Arena in Cleveland, Ohio, is set for 6:10 p.m. ET. Alabama is a 5.5-point favorite in the latest Saint Mary's vs. Alabama odds from SportsLine consensus, while the over/under for total points scored is 149.5, up 1.5 from the opener. Alabama's over/under for total points scored is 77.5.

Before making any Saint Mary's vs. Alabama picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Saint Mary's vs. Alabama 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread cashes in well over 50% of simulations!

So who wins Saint Mary's vs. Alabama, and which side of the spread cashes in well over 50% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!