Saint Joseph's (4-3) and No. 6 Villanova (5-2) face off in an early afternoon tipoff on Saturday at noon ET. The Wildcats are on a two-game winning streak, defeating La Salle and Pennsylvania University this past week. The Hawks are also on a two-game win streak. In their last matchup against Binghamton, Saint Joseph won 79-57. Villanova is favored by 22 points at Caesers Sportsbook, while the Over-Under is set at 143.

Before making any Saint Joseph's vs. Villanova picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.  

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Villanova guard Collin Gillespie is averaging a team-best 17 points with 3.9 assists. Gillespie has also been shooting the ball well from downtown, hitting on 44 percent from 3-point land. The Pennsylvania native has hit at least three 3-pointers in six games this season. Against Howard, Gillespie scored 21 points and hit a season-high five 3-pointers. 

The model also knows Saint Joseph's forward Taylor Funk is averaging a team-high 17.4 points with 5.9 boards per game. The Pennsylvania native is shooting 55 percent from the field and 53 percent from beyond the arc. Funk has scored at least 12 points in six games thus far. Against Georgetown, Funk finished with 29 points, seven rebounds, and four steals. He was on fire from 3-point land and shot 8 of 10. 

Now, it has set its sights on Saint Joseph's vs. Villanova. We can tell you the model is leaning over the total and it also says one side of the spread hits in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Saint Joseph's vs. Villanova? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to find out which side of the Saint Joseph's vs. Villanova spread you should be all over Saturday, all from the model on a roll on college basketball picks!