The Memphis Tigers will look to get back into the win column when they battle the Rice Owls in a key American Athletic Conference matchup on Friday night. Memphis had its four game-winning streak stopped with a 44-36 loss at UTSA on Saturday, while Rice defeated Navy 24-10. The Owls (3-6, 2-3 AAC), who are tied for eighth in the conference, are 0-4 on the road this season. The Tigers (7-2, 3-2 AAC), who are fourth in the league, are 5-0 on their home field in 2024.

Kickoff is set for 9 p.m. ET at Simmons Bank Liberty Stadium in Memphis. The teams will be playing each other for the first time since 2012, a 14-10 Memphis win. The Tigers are 8-point favorites in the latest Rice vs. Memphis odds, while the over/under for total points scored is 51.

Before making any Memphis vs. Rice picks, check out the college football predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 18-9 on all top-rated picks over the past six weeks of this season. Anyone following has seen STRONG returns!

The model has simulated Memphis vs. Rice 10,000 times and the results are in. We can tell you the model is leaning Over on the total, and it also says one side of the spread hits in over 60% of simulations!

Who wins Memphis vs. Rice, and which side of the spread cashes in over 60% of simulations? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model that is 18-9 over the past six weeks on top-rated CFB picks!