Real Madrid and RB Leipzig rematch in the second leg of the UEFA Champions League Round of 16 on Wednesday on Paramount+. Los Blancos won the first leg of the competition on the road 1-0, and the competition shifts to their home pitch where they have won six of their last seven matches across all competition. They host a Leipzig side that looks to overcome its road woes after getting a 4-1 road win in league play over the weekend. You can stream the match live on Paramount+, which you can now try free for the first seven days. 

Kickoff from Santiago Bernabeu Stadium in Madrid is set for 3 p.m. ET. The latest Real Madrid vs. RB Leipzig odds list the Spanish side as -180 favorites (risk $180 to win $100) on the 90-minute money line, with Leipzig listed as +425 underdogs. A draw is priced at +340 and the over/under for total goals is 3.5. Wednesday's match will be streamed live on Paramount+ with their must-have Premium plan, which you can now try FREE for the first week.

Paramount+ is the only place to watch every minute of every UEFA Champions League match this season. A subscription also gives you access to other sports content including Europa League, Serie A, NWSL, NFL on CBS, and countless movies and shows. You can get your first week free, so sign up right here.

Before you bet on Real Madrid vs. RB Leipzig or make any other UEFA Champions League predictions, you must see what SportsLine's soccer insider Martin Green has to say.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since last year's World Cup, Green has been profitable in multiple areas on his soccer picks, including the Champions League (+4.78 units), the FA Cup (+3.07), the EFL Cup (+3.64), Euro 2024 qualifiers (+3.01) and the Europa League (+1.60).

Green has taken an in-depth look at the Real Madrid vs. Leipzig showdown and he has locked in a pair of CONFIDENT best bets while offering a full breakdown of this Champions League matchup! You ABSOLUTELY need to see his pick and analysis before making any selections of your own. Don't forget to stream the match on Paramount+, where you can watch over 2,400 soccer matches a year.

So who wins RB Leipzig vs. Real Madrid in the UEFA Champions League Round of 16? And where does all the betting value lie? ... Join SportsLine now to see Martin Green's picks for RB Leipzig vs. Real Madrid, all from the insider who has his finger on the pulse of the game all over the world!