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Real Madrid vs. Atletico Madrid odds, Round of 16 prediction: UEFA Champions League picks, best bets for March 4, 2025

SportsLine soccer expert Brandt Sutton has locked in his Champions League picks for Atletico Madrid vs. Real Madrid on Tuesday

A heated rivalry is set to renew in the UEFA Champions League when Real Madrid host Atletico Madrid for the first leg of the Round of 16 clash Tuesday on Paramount+. Real Madrid knocked off Manchester City 6-3 on aggregate thanks to Kylian Mbappe's hat trick in the second leg. Atletico Madrid advanced directly to the Round of 16 after winning six of their first eight matches in this competition. Stream the match live on Paramount+, which you can now try free for the first seven days when you sign up here.

Kickoff from Santiago Bernabéu in Madrid is set for 3 p.m. ET. The latest Real Madrid vs. Atletico Madrid odds list the hosts as the -115 favorites (risk $115 to win $100) on the 90-minute money line, with Atletico Madrid the +330 underdogs. A draw is priced at +260, and the over/under for total goals is 2.5. Tuesday's match will be on Paramount+, which is free for the first week when you sign up here.

Paramount+ is the place to watch the Champions League this season. A subscription also gives you access to other sports content, including the UEFA Europa League, Serie A, EFL League One, NFL on CBS, Big Ten on CBS and countless movies and shows. You can now get a free 7-day trial, so sign up right here. 

Before you lock in your Real Madrid vs. Atletico Madrid picks or make any UEFA Champions League predictions, you need to see what proven soccer expert Brandt Sutton has to say.

Sutton, a former collegiate soccer player, has been SportsLine's top soccer editor for more than seven years. He has followed soccer closely for much longer and factors in managerial tactics, projected lineups and past performances to make the most informed decisions possible, keeping his finger on the pulse of the game all over the globe.

Sutton was SportsLine's top soccer expert in 2022 with a 165-130-2 mark with his soccer picks, returning nearly $2,200 for $100 players. He was also profitable across multiple leagues in 2023, including the English Premier League, UEFA Champions League, FA Cup, Europa League and more.

Sutton has taken an in-depth look at the Real Madrid vs. Atletico Madrid match and has locked in a CONFIDENT best bet while offering a full breakdown of this Champions League matchup! You ABSOLUTELY need to see his pick and analysis before making any selections of your own. Don't forget to stream the match on Paramount+.

So where does all the betting value lie for Real Madrid vs. Atletico Madrid in the UEFA Champions League Round of 16? ... Join SportsLine now to see Brandt Sutton's picks for Atletico Madrid vs. Real Madrid, all from the insider who is tuned into leagues all over the world!

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Brandt Sutton
Brandt SuttonFutbol Guy

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