Week 5 of the 2021 NFL schedule begins on Thursday Night Football with a divisional matchup between the Los Angeles Rams and Seattle Seahawks. Kickoff in Seattle is set for 8:20 p.m. ET. The Rams are favored by 2.5 points in the latest Rams vs. Seahawks odds from Caesars Sportsbook, while the over-under is 54.5.

Before you make any Rams vs. Seahawks picks or any other NFL predictions, you NEED to see which side SportsLine expert R.J. White is on. 

White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. He is also outstanding in handicapping the Rams, going 35-17-1 on his last 53 picks, returning more than $1,500. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. Anyone who has followed his picks has seen HUGE returns.

White knows the Rams are excelling on offense so far this season. Los Angeles is leading the NFL in scoring on 58.6 percent of its offensive possessions, and the Rams are also No. 1 in averaging 3.28 points per drive. The passing connection between quarterback Matthew Stafford and wide receiver Cooper Kupp is generating video game numbers, and the Rams have a talented defense that led the league in points allowed and yards allowed in 2020.

On the other side, the Seahawks quarterback Russell Wilson leads the NFL in passer rating (129.9) and yards per pass attempt (9.6). He is the centerpiece of an offensive that ranks near the top of the NFL in touchdown passes, rushing touchdowns, yards per pass, yards per carry and yards per drive.

Now, White has locked in another confident against the spread pick for Rams vs. Seahawks. We can tell you he's leaning over the total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Rams vs. Seahawks on Thursday Night Football? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Rams vs. Seahawks spread to jump on, all from the expert who's an outstanding 35-17 on Rams picks!