The Arizona Cardinals (10-2) will host the Los Angeles Rams (8-4) on Monday Night Football and can inch closer to the NFC West crown and the NFC's top seed with a victory. Kickoff is set for 8:15 p.m. ET at State Farm Stadium. The Cardinals are favored by three points in the latest Rams vs. Cardinals odds from Caesars Sportsbook, while the over-under is 51.

Before you make any Cardinals vs. Rams picks or NFL predictions, you NEED to see which side SportsLine expert R.J. White is on. 

White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest.

In addition, White has gone an astounding 36-21-1 on his last 58 picks involving the Rams, returning almost $1,300 for $100 bettors. Anyone who has followed him is way up.

The Cardinals boast a top-10 offense and are third in the NFL in scoring. Quarterback Kyler Murray is completing almost 73 percent of his passes and averages 267 passing yards per game. He started last week along with wide receiver DeAndre Hopkins (518 yards, eight TDs in nine games). Running back James Conner also has been effective, posting 842 total yards and 14 TDs this season.

Los Angeles quarterback Matthew Stafford is third in passing yards (3,611) and second in TD passes (30). Cooper Kupp has been nearly impossible to stop with Stafford in the mix, leading the league with 113.8 receiving yards per game. Sony Michel rushed for 121 yards last week and will be the featured back again on Monday with Darrell Henderson sidelined due to COVID-19.

White has locked in another confident pick against the spread for Rams vs. Cardinals. We can tell you he's leaning Over the total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Rams vs. Cardinals on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Cardinals vs. Rams spread to jump on, all from the expert who's an outstanding 36-21 on Rams picks!